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Gemifioxacin mesylate
CAS No. 210353-53-0
Gemifioxacin mesylate( LB 20304a | SB 265805S )
Catalog No. M13343 CAS No. 210353-53-0
Gemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
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| 10MG | 42 | In Stock |
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| 25MG | 70 | In Stock |
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| 50MG | 105 | In Stock |
|
| 100MG | 150 | In Stock |
|
| 200MG | 223 | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGemifioxacin mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionGemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.
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DescriptionGemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.(In Vitro):Gemifloxacin has higher antibacterial activity than Moxifloxacin (HY-66011A) against Streptococcus pneumoniae with a MIC90 of 0.06 μg/mL.Gemifloxacin has highly potent antibacterial activity against Penicillin-resistant strains of S. pneumoniae with a MIC90 of 0.03 μg/mL.(In Vivo):Gemifloxacin has favorable pharmacokinetic profile in animals after oral administration.
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In VitroGemifloxacin has higher antibacterial activity than Moxifloxacin (HY-66011A) against Streptococcus pneumoniae with a MIC90 of 0.06 μg/mL.Gemifloxacin has highly potent antibacterial activity against Penicillin-resistant strains of S. pneumoniae with a MIC90 of 0.03 μg/mL.
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In VivoGemifloxacin has favorable pharmacokinetic profile in animals after oral administration.Pharmacokinetic Parameters of Gemifloxacin in Sprague-Dawley rats and dogs.
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SynonymsLB 20304a | SB 265805S
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PathwayCell Cycle/DNA Damage
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TargetDNA gyrase
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RecptorDNA gyrase| Topo II
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number210353-53-0
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Formula Weight485.49
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Molecular FormulaC19H24FN5O7S
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Purity>98% (HPLC)
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SolubilityDMSO: 30mg/mL
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SMILESCO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O
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Chemical Name7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ruiz J, et al. Int J Antimicrob Agents. 2003 Jul;22(1):73-6.
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